{"id":528,"date":"2021-05-16T11:00:00","date_gmt":"2021-05-16T10:00:00","guid":{"rendered":"https:\/\/biopedia.co.uk\/?p=528"},"modified":"2021-07-22T14:34:46","modified_gmt":"2021-07-22T13:34:46","slug":"32-trisomies-and-non-disjunction","status":"publish","type":"post","link":"http:\/\/biopedia.co.uk\/?p=528","title":{"rendered":"32- Trisomies and Non-Disjunction"},"content":{"rendered":"\n<figure class=\"wp-block-embed is-type-rich is-provider-spotify wp-block-embed-spotify wp-embed-aspect-21-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Spotify Embed: 32- Trisomies and Non-Disjunction\" width=\"100%\" height=\"232\" allowtransparency=\"true\" frameborder=\"0\" allow=\"encrypted-media\" src=\"https:\/\/open.spotify.com\/embed\/episode\/4ksnAPr75LBh9o0WR1CEDU\"><\/iframe>\n<\/div><\/figure>\n\n\n<p>Usually, we get two copies of each chromosome. However, the finely tuned process of meiosis and fertilisation can go awry such that a new zygote ends up with three copies. Depending on the chromosome, this can have serious consequences&#8230;<\/p>\n<p>Sources for this episode: 1) For an explanation of non-disjunction which I found helpful when I was at sixth form, see: Amoeba Sisters, YouTube (2017), Meiosis (Updated) (online) [Accessed 25\/03\/2021]. 2) NHS website, Edwards&#8217; syndrome (trisomy 18) (online) [Accessed 25\/03\/2021]. 3) Xu, X., Zhang, X., Han, J.-W., Adamu, Y. and Zhang, B. (2020), Potential Increased Risk of Trisomy 18 Observed After a Fertilizer Warehouse Fire in Brazos County and TX. International Journal of Environmental Research and Public Health 17: 2561- 2571.<\/p>","protected":false},"excerpt":{"rendered":"<p>Usually, we get two copies of each chromosome. However, the finely tuned process of meiosis and fertilisation can go awry such that a new zygote ends up with three copies. Depending on the chromosome, this can have serious consequences&#8230; Sources for this episode: 1) For an explanation of non-disjunction which I found helpful when I &hellip; <\/p>\n<p class=\"link-more\"><a href=\"http:\/\/biopedia.co.uk\/?p=528\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;32- Trisomies and Non-Disjunction&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[5],"tags":[],"_links":{"self":[{"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/posts\/528"}],"collection":[{"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=528"}],"version-history":[{"count":1,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/posts\/528\/revisions"}],"predecessor-version":[{"id":538,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=\/wp\/v2\/posts\/528\/revisions\/538"}],"wp:attachment":[{"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=528"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=528"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopedia.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}